Hydrophilic therapeutic agents exhibit poor membrane transport properties and present enormous challenges in drug delivery primarily due to their charge, size and stability characteristics. In absence of appreciable oral absorption, most current hydrophilic drugs must be delivered invasively.

Hydroance, Lipocine's lipid-based proprietary technology platform, offers non-invasive delivery solutions for small polar organics and macromolecules. Hydroance customizes lipid based carriers for the optimal presentation of the drug and absorption promoters to the absorption site, thus enabling absorption of the drug across the cell membranes of the intestinal tract.

Hydroance is a wide range of proprietary compositions of bioacceptable absorption promoters and lipid excipients. Hydroance technology uses conventional manufacturing processes that are easy to scale-up. Hydroance enables oral delivery of compounds that are currently delivered only by the invasive route, such as small polar organics, peptides, polysaccharides, small peptides, peptido-mimetics and potentially vaccines.