Conventional controlled release technologies have been designed primarily for water soluble drugs. These technologies can be inherently inefficient for delivery of poorly water soluble drugs due to inadequate or pH sensitive solubilization/release or due to "absorption window" limitations. Such limitations often can result in inadequate absorption with reduced efficacy.

Lip'ral Synchronized Solubilizer Release (SSR) is an extension of the Lip'ral technology platform superimposing controlled release aspects while preserving the solubilizing power and absorption improvement of Lip'ral technology. Lip'ral SSR synchronizes the release of the solubilizers that require solubilization and controlled release.

Lip’ral SSR offers:

Diverse release profiles: can be modulated for extended release throughout the gastrointestinal (GI) tract or for delayed, extended, pulsatile or other forms of targeted release pH-independent solubilization: ideal for acidic and basic drugs requiring consistent absorption throughout the GI tract for safety or efficacy

Optimization: utilizes a wide range of proprietary compositions with bioacceptable excipients specifically designed for the physicochemical properties and pharmacokinetic requirements of a particular drug Conventional manufacturing Lip'ral SSR enables superior products with: Improved bioavailability/reduced dose Reduced dosing frequency/improved patient compliance Targeted absorption or chronotherapeutic release