LPCN 1144

Changing the Treatment of NASH

Finding A Solution to Fatty Liver Diseases

Team of Research Scientists Working With Personal Computer, Anal

Targeted For Non-Alcoholic Steatohepatitis (NASH)

LPCN 1144, an oral prodrug of bioidentical testosterone, is being developed as a treatment for pre-cirrhotic non-alcoholic steatohepatitis ("NASH") and recently completed a Phase 2 paired biopsy NASH confirmed clinical study.

Rationale to Target Non-Cirrhotic Male NASH Patients
Association Between Testosterone and Liver Disease
Clinical Evidence of Association Between Testosterone and Liver Disease
LPCN 1144:  Androgen Receptor Agonist
LPCN 1144: A Differentiated NASH Treatment Candidate
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LFS was an open-label, multi-center single-arm 16-week study (N=36) with LPCN 1144 in hypogonadal males
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*LF = Liver Fat

Meaningful Relative Liver Fat % Change and Responder Rate
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* Responder rate for relative change is % of patients with at least 30% for relative change from baseline. 

Liver Fat-Based Subject Distribution at Each Visit
Longer Therapy Improved Proportion of Subjects with Disease Resolution
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Innovative Pharmaceutical Products

ENHANCING HEALTH & IMPROVING PATIENT COMPLIANCE

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